Prof. Dr. Jolanda Kluin

Tissue Engineered Heart Valves and Hybrid Hearts

by Professor Dr. Jolanda Kluin Academic Medical Center, Amsterdam

Jolanda Kluin will focus on her research on heart valve tissue engineering. Besides presenting scientific results, she will discuss the difficulties the research group faces and the many little steps that are needed in the long road from bench to bed-side. Besides, she will tell about her Hybrid Heart project (the development of a soft robotic total artificial heart). She cannot present all the results yet but she will take you with her on her journey to achieve the consortium’s goal.  The collaboration between physicians and engineers, physicists, chemists etc will be highlighted as she strongly believes that this is of utmost importance.

Jolanda Kluin studied medicine at the Erasmus University Rotterdam. As a PhD student she worked on the project: “Photodynamic therapy for Barrett’s oesophagus with use of 5-aminolevulinic acid”. She received several awards for her research and in December 1999 she received her PhD degree cum laude.  In 2006 she finished her residency in cardiothoracic surgery and became a staff surgeon at the Department of Cardiothoracic Surgery of the UMC Utrecht. Since 2015 she works as cardiac surgeon at the AMC Amsterdam Reconstructive valve surgery and surgery of the aorta have her special interest. 
Next to her clinical tasks she extensively participates in research. Her main research topic is tissue-engineering of heart valves, this in close collaboration with the Eindhoven University of Technology. Heart valve biology in general and modern imaging techniques are other topics. In 2017 she became the PI of a FET-open rewarded consortium that envisions to develop a soft robotics heart. Since 2018 she is professor Translational Cardiothoracic Surgery at the University of Amsterdam.

Prof. Luca Mainardi

Novel techniques and digital biomarkers processing for non-contact and nonintrusive screening of Atrial Fibrillation

by Prof. Luca Mainardi, Politecnico di Milano

Abstract.  Atrial Fibrillation (AF) is the most common sustained disorder of cardiac rhythm and is estimated to affect 1.5%-2% of the general population with a prevalence that increases with age, and reaches nearly 10% in octogenarians. Considering the aging population, the disease is reaching a pandemic proportion which stimulates the development of methodology and technologies for the investigation of AF events in large populations both for screening purposes and for monitoring the efficiency of treatment/therapy. The talk will describe modern signal processing and modelling techniques applied to a variety of biosignals acquired in AF patients using novel technologies (wristband devices or contactless measurements) and will provide an overview of the contributes of those methods in solving the challenging problems of AF patient screening and management.

Mainardi Luca is Professor at the Dipartimento di Elettronica, Informazione e Bioingegneria of the Politecnico di Milano, Italy. Co-chair of the SPiNlabS Laboratory at Politecnico di Milano, his research activity is in the field of biomedical signal and image processing and biomedical system modeling with applications to the cardiovascular system. He studies and develops methods for time-frequency analysis, recursive parametric identification and non-linear analysis of cardiovascular signals and series, with interest in the investigation of Atrial Fibrillation. He also studies advanced biomedical image processing techniques for features extraction, image registration and Radiomics for oncology applications. He is the author of more than 140 peer reviewed papers in international journals. He authored 12 book chapters and is editor of the book “Understanding Atrial Fibrillation: the signal processing Contribute” published by Morgan&Claypool, USA.
He is a member of the Editorial Board of the journal “Biomedical Engineering – Biomedizinische Technik” (deGruyter) and member of the International Advisory Board of the Journal “Physiological Measurements” (IOPScience). Member of the Directory Board of the Italian National Group of Bioengineering (GNB) in the period 2004-2007, he is the elected Chair of the International Medical Informatics Association (IMIA) WG7 on Biomedical Pattern Recognition. He is elected -Chair of the EMBS Technical Committee on Biomedical Signal Processing (2018-2020) and member of the Board of “Computing in Cardiology” (CinC) annual Conference.  He is the Coordinator of the EU Marie-Curie project MY-ATRIA under the H2020 program framework (GA-766082).